Mayo Clinic does not endorse companies or products. This content does not have an Arabic version. Sildenafil ( Viagra ), tadalafil ( Cialis ), avanafil ( Stendra ),and vardenafil ( Levitra) increase the blood pressure lowering effects of isosorbide mononitrate and may cause excessive reductions in blood pressure. Some people feel dizzy or fall when changing positions, such as going from sitting to standing. Isosorbide mononitrate is also sometimes prescribed alongside other medicines for people with heart failure. What happens if I stop taking isosorbide mononitrate (Monoket)? My EKG showed Assess your symptoms online with our free symptom checker. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.AvanafilRiociguatSildenafilTadalafilVardenafil. In Canada - Call your doctor for medical advice about side effects. https://naturalmedicines.therapeuticresearch.com. Isosorbide can only be used to prevent angina; it cannot be used to treat an episode of angina once it has begun. Isosorbide mononitrate Alternatives Compared - Drugs.com Would you like email updates of new search results? 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). View more, Nitroglycerin dilates veins, relieving chest pain and lowering blood pressure. This information is aggregated and used to produce personalized reports that patients can reference. Yes, it's good for health but don't take it excesse in amount, use once daily for 1 month then stop it or take once a weekly. It works by relaxing the blood vessels so the heart does not need to work as hard and therefore does not need as much oxygen. Generic alternatives may be available. Isosorbide mononitrate systemic 60 mg (A ID). Nitrates | Prescribing information | Angina | CKS | NICE This survey is being conducted by the WebMD marketing sciences department. Ask your doctor before using aspirin together with alcohol. Isosorbide mononitrate belongs to the group of medicines called nitrates. Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Alternative cancer treatments: 11 options to consider. Commonly reported side effects include: See also: isosorbide mononitrate side effects in more detail. To help you remember, take it at the same times each day. Erectile dysfunction medications (e.g., sildenafil (Viagra), vardenafil (Levitra), tadalafil (Cialis)) cannot be taken while you're taking isosorbide mononitrate (Monoket). Talk to your pharmacist for more details. Be sure to talk to your health care provider before you take any herbal supplements if you take prescription medicines. This medication belongs to a class of drugs known as. Isosorbide comes as a tablet, an extended-release (long-acting) tablet, and an extended-release capsule to take by mouth. 1998-2023 Mayo Foundation for Medical Education and Research (MFMER). A very serious allergic reaction to this drug is rare. 1996 Dec;3(12):802-806. doi: 10.1097/00045391-199612000-00003. Talk to your doctor about the possible risks of using this medication for your condition. Discuss the risks and benefits with your doctor. 2021 May 11;39:28. doi: 10.11604/pamj.2021.39.28.22180. https://naturalmedicines.therapeuticresearch.com. The information eHealthMe analyzes includes: Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. Headache is often a sign that this medication is working. During pregnancy, this medication should be used only when clearly needed. Isosorbide mononitrate | Drugs | BNF | NICE All rights reserved. Herbal supplements are natural, so they must be safe, right? (1) Starting on a low dosage was associated with a reduced frequency and severity of headache and did not notably influence the beneficial effect on angina pectoris. Anti-ischemic and anti-anginal effects of controlled-release and conventional isosorbide-5-mononitrate in stable angina pectoris. Natural Medicines. Never take more than the prescribed dose. information is beneficial, we may combine your email and website usage information with It relaxes blood vessels in your body (causing them to widen) and this reduces the strain on your heart, making it easier for your heart to pump blood around your body. Once- versus twice-daily administration of controlled-release isosorbide-5-mononitrate 60 mg in the treatment of stable angina pectoris. If you experience any other symptoms which you think may be due to the medicine, please speak with your doctor or pharmacist for further advice. This should pass after a few days. Although unlikely, when this medication is used for a long time, it may not work as well and may require different dosing. Isosorbide mononitrate (Monoket) is not known to affect the kidneys. Check with your doctor immediately if any of the following side effects occur: burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings, dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position, fast, slow, irregular, pounding, or racing heartbeat or pulse, itching, pain, redness, or swelling on the leg, numbness or tingling in the hands, feet, or lips, pain or discomfort in the arms, jaw, back, or neck, pain, tension, and weakness upon walking that subsides during periods of rest, shakiness in the legs, arms, hands, or feet, swelling of the face, fingers, feet, or lower legs, trembling or shaking of the hands or feet, vomiting of blood or material that looks like coffee grounds, Bluish-colored lips, fingernails, or palms. Take extra precautions to avoid falling during your treatment with isosorbide. 1994 Jan;15(1):108-13. doi: 10.1093/oxfordjournals.eurheartj.a060361. coma (loss of consciousness for a period of time). It will give you more information about nitrate medicines, and it will also provide you with a full list of side-effects which you could experience from taking isosorbide mononitrate. No, that's not true all the time. Keep this medication in the container it came in, tightly closed, and out of reach of children. Pregnancy:Data on the use of isosorbide mononitrate during pregnancy are insufficient to be able to assess the possible harmful effect. Yet many herbal supplements may interact with heart disease medicines. If we combine this information with your protected Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Manufacturer's PIL, Imdur 60 mg tablets; TopRidge Pharma Ltd, The electronic Medicines Compendium. This medication performs a vasodilatory function and is therefore used as a treatment for high blood pressure. Swallow the extended-release tablets or capsules whole; do not crush, chew, or divide them. Synthroid (levothyroxine) Tylenol (acetaminophen) Vitamin B12 (cyanocobalamin) Vitamin C (ascorbic acid) Vitamin D3 (cholecalciferol) Isosorbide mononitrate disease interactions There are 7 disease interactions with isosorbide mononitrate which include: AMI anemia hemodialysis hypotension intracranial pressure hypertrophic cardiomyopathy glaucoma Herbal supplements and heart medicines may not mix - Mayo Clinic The body tends to develop a tolerance (decreased sensitivity) to ISMN when it is used continuously over 24 hours. FOIA Coenzyme Q-10 Natural Medicines. For these reasons, before you start taking isosorbide mononitrate it is important that your doctor knows: Along with their useful effects, most medicines can cause unwanted side-effects although not everyone experiences them. If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Careers. Patient is a UK registered trade mark. Do not let anyone else take your medication. Properly discard this product when it is expired or no longer needed. If headaches continue or become severe, tell your doctor promptly. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Longer-acting tablets and capsules are taken once daily in the morning. It has a very short duration of action and may not be suitable for some people. This site complies with the HONcode standard for trustworthy health information: verify here. The list below does not include all possible drug interactions with isosorbide mononitrate (Monoket). It works and leaves the body quickly, so it needs to be taken twice a day. MeSH Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Using this medicine with any of the following medicines is not recommended. isosorbide mononitrate (Imdur, Ismo, Monoket) - MedicineNet 72% of reviewers reported a positive effect, while 12% reported a negative effect. Selected from data included with permission and copyrighted by First Databank, Inc. Manufacturer's PIL, Isosorbide mononitrate 10 mg tablets; Merus Labs Luxco S.a.R.L, The electronic Medicines Compendium. The unwanted effects often improve as your body adjusts to the new medicine, but speak with your doctor or pharmacist if any of the following continue or become troublesome. Unneeded medications should be disposed of in special ways to ensure that pets, children, and other people cannot consume them. May also be prescribed off label for Esophageal Spasm. The PubMed wordmark and PubMed logo are registered trademarks of the U.S. Department of Health and Human Services (HHS). Isosorbide Mononitrate (Oral Route) - Mayo Clinic tell your doctor if you are taking or have recently taken riociguat (Adempas) or a phosphodiesterase inhibitor (PDE-5) such as avanafil (Stendra), sildenafil (Revatio, Viagra), tadalafil (Adcirca, Cialis), and vardenafil (Levitra, Staxyn). 45, Migranal), ergoloid mesylates (Hydergine), ergotamine (in Cafergot, in Migergot), methylergonovine (Methergine), methysergide (Sansert; no longer available in the U.S.), and pergolide (Permax; no longer available in the U.S.); medications for high blood pressure, heart failure, or an irregular heartbeat. privacy practices. health information, we will treat all of that information as protected health Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. It might help to keep the room cool and use a fan. Good at preventing chest pain caused by heart disease, Available as a generic version, making it less expensive, Long-acting version only needs to be taken once daily, Short-acting tablets have to be taken on a very specific schedule for the medication to work best. If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. See also: aspirin side effects in more detail. Unless there is a specific reason you need the brand, the generic medication will be a better value. The most common side-effect is headache. Do not share this medication with others. This activity describes the indications, action, and contraindications for isosorbide as a valuable agent in treating angina pectoris due to coronary artery disease, heart failure with reduced . What You Need to Know, Angina (a specific type of chest pain) caused by heart disease. Saw palmetto might make your risk of bleeding higher if you also take a blood thinner, such as: It's not suggested to take St. John's wort if you take blood thinners. Drug interactions may change how your medications work or increase your risk for serious side effects. Only your doctor, nurse, or pharmacist can provide you with advice on what is safe and effective for you. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. There are a number of medications that your doctor can prescribe in place of isosorbide mononitrate (Monoket). What are the side effects of Isosorbide Mononitrate ? Saper RB. Fish Oil (omega-3 polyunsaturated fatty acids), Email this report to a friend, doctor, or patient, isosorbide mononitrate consumer information. Before using this medication, tell your doctor or pharmacist your medical history, especially of: low blood pressure. 2006 Apr;95(4):217-23. doi: 10.1007/s00392-006-0367-x. Copyright, 2023. If it is within 2 hours of the next dose, skip the missed dose. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. You could also spray your face with cool water or sip non-alcoholic cold or iced drinks. All rights reserved. Isosorbide mononitrate helps to prevent angina chest pain from developing. Do not start, stop, or change the dosage of any medicines without your doctor's approval. DUMQOL (DUtch Mononitrate Quality of Life) Study Group. We comply with the HONcode standard for trustworthy health information. Isosorbide extended-release (long-acting) tablets and extended-release capsules are used for the management of chest pain in people who have coronary artery disease. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes. It will not treat an angina attack that has already begun. It is important that you follow the instructions your doctor gives to you about when to take your doses. Patient does not provide medical advice, diagnosis or treatment. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. Headache, dizziness, lightheadedness, nausea, and flushing may occur as your body adjusts to this medication. Natural Medicines. Below is the list of medicines, which contains Isosorbide Mononitrate as ingredient. Are you looking for information on isosorbide dinitrate (Isordil) instead? Mehta D. Botanical medicines. 2005 - 2023 WebMD LLC. Your doctor will probably tell you not to take isosorbide if you are taking one of these medications. Along with its needed effects, a medicine may cause some unwanted effects. McGraw Hill; 2022. https://accessmedicine.mhmedical.com/search. [2] It can be used both to treat and to prevent heart-related chest pain; however, it is generally less preferred than beta blockers or calcium channel blockers. Cleophas TJ, Niemeyer MG, van Der Wall EE. To avoid this problem, get up slowly, resting your feet on the floor for a few minutes before standing up. Therefore, oral nitrates should not be used by patients who are sensitive to the effects of hypotension, such as those with pre-existing hypotension, shock, vascular collapse or significant cerebrovascular disease, significant anaemia or hypothyroidism. Does Isosorbide Mononitrate interact with other drugs you are taking? Please upgrade your browser or download modern browsers from here! Journal of the American College of Cardiology. This is called a medicine interaction. Federal government websites often end in .gov or .mil. Your body can get used to isosorbide mononitrate (Monoket), and the same amount of medication might no longer work as well as it used to. Isosorbide mononitrate (Monoket) can cause headaches, dizziness, or lightheadedness. Side effects : headache, mild dizziness May also be prescribed off label for Esophageal Spasm. Isosorbide mononitrate helps to prevent angina chest pain from developing. Liperoti R, et al. So get a ct scan brain apart from cardiology workup. You may report side effects to Health Canada at 1-866-234-2345. I took this for 4 days, and my headaches were unbearable. Isosorbide Mononitrate ER Oral: Uses, Side Effects - WebMD It is used to treat and prevent a wide range of different conditions. Isosorbide mononitrate Interactions - Drugs.com Follow directions about how much medicine to take. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to similar drugs (such as isosorbide dinitrate, nitroglycerin); or if you have any other allergies. If you forget to take a dose, take it as soon as you remember. Take isosorbide exactly as directed. (3) The overall number of headache attacks in the first period of active treatment was significantly higher than in the second period irrespective of the dosages given. Isosorbide mononitrate dilates (widens) blood vessels, making it easier for blood to flow through them and easier for the heart to pump.Isosorbide mononitrate is used to prevent angina attacks (chest pain). information submitted for this request. This site complies with the HONcode standard for trustworthy health information: verify here. View all Isosorbide mononitrate has an average rating of Now, youll enjoy a streamlined experience created specifically for healthcare providers. Natural Medicines. If you have an eye condition called glaucoma. You may opt-out of email communications at any time by clicking on View interaction reports for isosorbide mononitrate and the medicines listed below. Angina pain develops if part of your heart muscle does not get as much blood and oxygen as it needs. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Isosorbide mononitrate is very similar to isosorbide dinitrate. GoodRx works to make its website accessible to all, including those with disabilities. Isosorbide tablets are also used with other medications to treat heart failure. eCollection 2021. This makes it easier for your heart to pump, relieving heart-related chest pain. Sept. 26, 2022. 19 are major, 174 are moderate, and 2 are minor. All rights reserved. Let your provider know if they are excessive. Isosorbide dinitrate (Isordil): Basics, Side Effects & Reviews - GoodRx Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press. When used regularly on a long-term basis, this helps prevent angina attacks from occurring. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less commonAcid or sour stomachanxietyback painbelchingblemishes on the skinbloatedbreast painburning feeling in the chest or stomachburning, dry, or itching eyeschange in color visionchanges in visioncold sweatscongestionconstipationcontinuing ringing or buzzing or other unexplained noise in the earscough producing mucusdecreased interest in sexual intercoursedifficulty seeing at nightdifficulty with movingdischarge, excessive tearingdouble visiondrooping upper eyelidsdull ache or feeling of pressure or heaviness in the legsearacheexcess air or gas in the stomach or intestinesfeeling of constant movement of self or surroundingsfeeling of warmthfeeling unusually coldfrequent urge to defecatefrozen shoulderfull feelinghearing lossheartburnhyperventilationinability to have or keep an erectionincreased appetiteincreased sensitivity of the eyes to sunlightincreased sputumindigestionirritabilityitching skin near damaged veinslack or loss of strengthloss in sexual ability, desire, drive, or performancemuscle or bone painmuscle stiffness or weaknessnightmaresnoisy breathingpain or tenderness around the eyes and cheekbonespassing gaspimplespoor concentrationrashredness of the face, neck, arms, and occasionally, upper chestredness, pain, swelling of the eye, eyelid, or inner lining of the eyelidredness, swelling, or soreness of the tonguerestlessnessseeing doublesensation of spinningsleepiness or unusual drowsinesssmall clicking, bubbling, or rattling sounds in the lung when listening with a stethoscopesmall lumps under the skinsore mouth or tonguestiff neckstomach bloating, burning, cramping, or painstomach discomfort or upsetstraining while passing stoolstuffy nosesudden sweatingswollen feet and anklestender, swollen glands in the necktenderness in the stomach areaterrifying dreams causing sleep disturbancestooth disordertrouble swallowinguncontrolled twisting movements of the neckvoice changesweight losswhite patches in the mouth, tongue, or throatOther side effects not listed may also occur in some patients. It works more slowly and lasts for about 12 hours, so you only need to take it once a day. Stopping isosorbide mononitrate (Monoket) suddenly can cause you to have a worsening of your chest pain. Accessed Sept. 7, 2022. The IR version can help treat and prevent angina. Isosorbide mononitrate tablets and capsules are not suitable to take to treat the pain of an angina attack. To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position. 5.0 out of 10 from a total of Data sources include IBM Watson Micromedex (updated 5 Feb 2023), Cerner Multum (updated 22 Feb 2023), ASHP (updated 12 Feb 2023) and others. 88 ratings on Drugs.com. It is not a substitute for a medical exam, nor does it replace the need for services provided by medical professionals. you should know that you may experience headaches every day during your treatment with isosorbide. Advertising revenue supports our not-for-profit mission. other information we have about you. Prescribed for Angina, Anal Fissure and Higher than recommend dosage of sublingual isosorbide dinitrate for treating angina pectoris: a case report and review of the literature. Is it safe to drive while on this medicine? Available for Android and iOS devices. Alternative drugs to the conditions Isosorbide mononitrate treats: Angina High blood pressure Stable angina Chest pain Heart disease Heart attack Angina unstable Heart disease congenital Coronary heart disease Heart failure Pulse Heart rate irregular Coronary artery spasm Angioplasty Please note that only the generic name of each medication is listed below. Isosorbide Manufacturing: An In-Depth Look at Production Costs and Can isosorbide mononitrate cause problems? Store in a cool, dry place, away from direct heat and light. Isosorbide Mononitrate - Medicine.com sharing sensitive information, make sure youre on a federal Make sure laboratory personnel and all your doctors know you use this drug. If you have an underactive thyroid gland. Minimally clinically significant. Accessibility https://naturalmedicines.therapeuticresearch.com. Prescribed for Angina, Heart Failure, Angina Pectoris Prophylaxis. Tell your doctor if this medication stops working well (for example, you have more frequent or worsening chest pain). Take the container with you, even if it is empty. Botanical medicine A modern perspective. Unable to load your collection due to an error, Unable to load your delegates due to an error. Consult your doctor for more details. For haemoglobin formation vit. If your chest pain attacks happen more often, last longer, or become more severe at any time during your treatment, call your doctor. Prescription and OTC Aspirin relieves pain and inflammation and helps to thin the blood. Your doctor will tell you which is the right dose for you, and this will also be printed on the label of the pack to remind you about what the doctor said to you.